level 6
Fig 5. Confocal laser microscopy after double staining with HB-GAM and cell marker antibodies in the spinal cord at 7 d after SCI. White arrowheads indicate cells double stained for HB-GAM (green) and respective cell marker (red), bIII-tubulin (A-C), GFAP (D-F), Rip (G-I), and OX-42 (J-L). (C, F, I, L) show the merge pictures (yellow). (M-O) show the control slides without primary antibodies.
2006年06月09日 15点06分
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level 6
这个应该就是肝素的化学结构了The breast cancer susceptibility protein BRCA2 controls the activity of the RAD51 recombinase in pathways that lead to DNA repair by homologous recombination. The structure of the RAD51 RecA-homology domain bound to BRC repeat 4 of BRCA2 shows that the BRC repeat mimicks a short RAD51 motif used by the recombinase to self-associate into a nucleoprotein filament, an essential intermediate of genetic recombination. BRCA2 thus controls RAD51 activity by acting as a binding antagonist to RAD51 filament formation.
2006年06月09日 15点06分
2
level 6
看错了，这才是上图的注释The FGFR - FGF - heparin complex [PDF] [medline] [coordinates (PDBid: 1E0O)] The Fibroblast Growth Factors (FGFs) are a large family of proteins with a pleiotropic range of physiological and pathological effects. In order to transmit a signal inside the cell, FGF assembles in a specific ternary complex with its transmembrane receptor tyrosine kinase (FGFR), and a low-affinity heparan sulphate (HS) receptor. The structure of the FGFR ectodomain bound to FGF and a HS-mimic heparin oligosaccharide defined the role of heparin in potentiating the affinity of the growth factor for its receptor, and demonstrated the mode of FGFR dimerisation, an essential prerequisite for transmembrane signalling.Reviewed in Current Opinion in Structural Biology.
2006年06月09日 15点06分
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level 4
困死了，再过半小时世界杯就开幕了。刚看到好久前德国佬给我发的modified 照片，好几张是偷拍的，照得我一点都不漂亮，唉～～～不过猴头终于见到他们的双胞胎小冬瓜了，哈哈～～
2006年06月09日 15点06分
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level 4
Figure 8: Acute hearing loss therapy by extracorporeal fibrinogen reduction With H.E.L.P.® apheresis (heparin-induced extracorporeal lipoprotein fibrinogen precipitation, B.Braun, Medizintechnologie GmbH, Germany) LDL, lipoprotein (a) and fibrinogen is precipitated and filtered out at an acid pH of 5.12 in the extracorporeal plasma circulation using heparin. The filtered plasma then passes a heparin adsorber and a dialyzer to remove the buffer. The reduction in high-molecular-weight plasma proteins achieved this way improves the rheological properties of the blood.
2006年06月10日 10点06分
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