要求程序非前台程序也有效，比如QQ的截图快捷键ctrl+alt+a懂的教下我，谢谢。

RegisterHotkey

再帮你找一片文章使用RegisterHotkey的概念是，它会定义一组或单个按键的组合，不管在哪个程序之中，按下程序窗体有注册的HotKey时，系统会传送WM_HOTKEY 的讯息给待接收该讯息的程序窗体，而该程序窗体接收到WM_HOTKEY时，便可知道有本身Thread所定义的HotKey被按下，於是可以从wParam, lParam来得知是哪一组HotKey被按下,从而执行相应的操作.函数声明的定义如下：RegisterHotKey( ByVal hwnd As Long , //接收自定义热键的窗口的HWND ByVal idHotKey as Long, //id为你自己定义的一个ID值对一个线程来讲其值必需在0x0000 - 0xBFFF范围之内,十进制为0~49151, 对DLL来讲其值必需在0xC000 - 0xFFFF 范围之内,十进制为49152~65535,在同一进程内该值必须唯一参数 fsModifiers指明与热键联合使用按键 ByVal Modifiers As Long, // 指明与热键联合使用按键(ALT,SHIFT,CTR的组合)如不需可置空,可取值为：MOD_ALT, MOD_CONTROL, MOD_WIN, MOD_SHIFT参数，或数字0为无，1为Alt,2为Control，4为Shift，8为Windows ByVal uVirtKey As Long //定主你自定的HOTKEY的虚拟按键码 )WM_HOTKEY 叁数的定义idHotKey = wParam; Modifiers = (UINT) LOWORD(lParam); uVirtKey = (UINT) HIWORD(lParam); 所以了，除了设定RegisterHotkey外，另要使用SubClassing的技巧才会得知HotKey被按下；最后，程序结束前要使用UnRegisterHotkey将HotKey的定义取消掉。切记,一定要有用有还!!!以下程序功能是：不管在哪个程序中，只要按下ALT-SHIFT-G 便执行NotePad。'以下在.BasOption ExplicitDeclare Function SetWindowLong Lib "user32" Alias "SetWindowLongA" _(ByVal hwnd As Long, ByVal nIndex As Long, ByVal dwNewLong As Long) As LongDeclare Function GetWindowLong Lib "user32" Alias "GetWindowLongA" _(ByVal hwnd As Long, ByVal nIndex As Long) As LongDeclare Function CallWindowProc Lib "user32" Alias "CallWindowProcA" _(ByVal lpPrevWndFunc As Long, ByVal hwnd As Long, ByVal Msg As Long, _ ByVal wParam As Long, ByVal lParam As Long) As LongDeclare Function RegisterHotKey Lib "user32" (ByVal hwnd As Long, ByVal id As Long, ByVal fsModifiers As Long, ByVal vk As Long) As LongDeclare Function UnregisterHotKey Lib "user32" (ByVal hwnd As Long, ByVal id As Long) As LongPublic Const WM_HOTKEY = &H312Public Const MOD_ALT = &H1Public Const MOD_CONTROL = &H2Public Const MOD_SHIFT = &H4Public Const GWL_WNDPROC = (-4)Public preWinProc As LongPublic Modifiers As Long, uVirtKey As Long, idHotKey As LongPrivate Type taLong ll As LongEnd TypePrivate Type t2Int lWord As Integer hword As IntegerEnd TypePublic Function wndproc(ByVal hwnd As Long, ByVal Msg As Long, _ ByVal wParam As Long, ByVal lParam As Long) As LongIf Msg = WM_HOTKEY Then If wParam = idHotKey Then Dim lp As taLong, i2 As t2Int lp.ll = lParam LSet i2 = lp If (i2.lWord = Modifiers) And i2.hword = uVirtKey Then ‘此处为接收到热键后需执行的操作 End If End IfEnd If'将之送往原来的Window Procedurewndproc = CallWindowProc(preWinProc, hwnd, Msg, wParam, lParam)End Function'以下在 FormSub Form_Load()Dim ret As LongpreWinProc = GetWindowLong(Me.hwnd, GWL_WNDPROC)ret = SetWindowLong(Me.hwnd, GWL_WNDPROC, AddressOf wndproc)idHotKey = 1 'in the range &h0000 through &hBFFFModifiers = MOD_ALT + MOD_SHIFTuVirtKey = vbKeyGret = RegisterHotKey(Me.hwnd, idHotKey, Modifiers, uVirtKey)End SubPrivate Sub Form_Unload(Cancel As Integer)Dim ret As Long'取消Message的截取，而使之又只送往原来的Window Procedureret = SetWindowLong(Me.hwnd, GWL_WNDPROC, preWinProc)Call UnregisterHotKey(Me.hwnd, uVirtKey)End Sub